Trip therapy: Depression treatment with psilocybin

Psilocybin and depression

The awareness that psilocybin sessions are a very strong treatment method against depression is increasing. Scientific studies are increasingly showing that psilocybin is most effective in treatment-resistant depression. All of these studies are based on a single high dose of psilocybin without lifestyle modifications. What would happen if all test subjects were also advised to adopt a healthier lifestyle outside of the psilocybin session?

The trip therapy treatment against depression

The majority of our clients suffer from depression. From the work experience of trip therapy, we learn that the results of depression treatments with psychedelics such as psilocybin work even better if we make a plan of action to promote physical and mental health. We do this in trip therapy based on an intake and neurotransmitter question test so that we can improve the neurochemistry of the brain before the psychedelic session. This together with some extra preparation ensures a good basis and a better psychedelic session.

For whom is psilocybin therapy not suitable?

Psilocybin and certain medications definitely cannot go together. There are also a few other physical contraindications that we should take into account. Furthermore, some mental illness can be aggravated by the use of psychedelics. Here are the contraindications.


  • High bloodpressure
  • Heart and vascular disease
  • Brain hemorrhages
  • Pregnancy


  • Schizophrenia
  • Psychosis(sensitivity)
  • Borderline


  • SSRi: citalopram (Cipramil®) – escitalopram (Lexapro®) – fluoxetine (Prozac®) – fluvoxamine (Fevarin®) – paroxetine (Seroxat®) – sertraline (Zoloft®) etc…
  • SNRI: Venlafaxine (Efexor) – Duloxetine (Cymbalta) etc…
  • TCA: mitriptyline (Tryptizol®) – clomipramine (Anafranil®) – imipramine – nortriptyline (Nortrilen®) etc….
  • Benzodiazepines: oxazepam (Seresta), – diazepam (Valium) – alprazolam (Xanax) etc…
  • Medicines for high blood pressure: (methyldopa, guanethidine, reserpine)
  • Tramadol and similar resources.

In case you use a medication that cannot be combined with psychedelics, you can examine in consultation with the prescribing doctor whether you can gradually reduce this medication. So never just stop taking medication without consulting your doctor. A psychedelic session can take place two weeks after complete abstinence from the above medicines.

The first steps in depression treatment

Step 1

Gradually we can call depression an inflammatory disease. The decrease in serotonin, dopamine and GABA is often a result of nutrient deficiencies and/or mild to severe inflammatory responses in the body. Precisely to trace the causes as much as possible, it is best to do as much good as possible. Let's start with a good diet that lowers the risk of nutrient deficiency and inflammation. Read the following blog for more information about the anti-depression diet.

The antidepressant diet

Step 2

If you are allergic to certain foods or substances in the environment, it is good to avoid them as much as possible. Allergies also increase the inflammatory values and thus the risk of depression. Requesting an allergy test can provide very useful information.

Step 3

During sleep, the body and brain are repaired. Sleeping well is an important factor. During sleep, a hormone called BDNF is released, which restores areas of the brain that have typically declined in health due to depression. BDNF appears to play a greater role in preventing depression in men than in women.

Tips for better sleep

Step 4

Take a look at the image below and assess which causes of stress and therefore inflammation you can eliminate. The more you do good, the better all parts of the fight against depression will work together.

Step 5

Implement our advice that we give after the registration of trip therapy for a period of 1-3 weeks.

Launch the intake for trip therapy here

Step 6

The psychedelic session causes changes on a physical level. New connections are created in the brain through neurogenesis. This effect in itself improves mood. In addition to these physical changes, insights gained during the psychedelic state can lead to changes in thinking and behavior. All these changes together provide the desired result. So change is the key to success in a world where the only thing that always stays the same is… change.

How many psilocybin sessions are needed?

For the treatment against depression, we only need 1 or 2 sessions for most clients, of which the first session is often dosed lower than the second. There is a period of approximately two months between these sessions. These two months are used to work with the insights. Everyone does this in their own way.

How have other people experienced trip therapy for depression?

We have a number of reviews on the forum from customers who have undergone a psilocybin session to combat depression. Here are the hyperlinks of a number of reviews:

Psilocybin Therapy Review

Trip therapy against depression

Trip against depression

Medium truffle trip against depression

Trip therapy in Schiedam

How can we help you?

Everyone is unique and needs a slightly different approach. What other goals do you have outside of depression treatment? Depression often goes hand in hand with anxiety. In any case, let us know your total place via the intake or contact form so that we can use a tailor-made approach.

The original post comes from the link below

Trip therapy against depression, anxiety, stress, burnout and PTSD: Depression treatment with psilocybin

Read more about our here psychedelic therapy in combination with treatment against depression, burnout, stress, fear, low self esteem, social anxiety, PTSD, insecurity and chronic inflammatory diseases.


Other names for psychedelic therapy: Ayahuasca, MDMA therapy, Truffle ceremony, mushroom ceremony, psilocybin ceremony.