MDMA therapy according to science

MDMA therapy is increasingly being explored as a therapeutic tool and is likely to be seen as a treatment for a variety of mental health conditions within a few years. According to science, MDMA therapy can mainly help with anxiety-related complaints. According to scientific research, MDMA therapy can help with the following conditions or situations.

  1. Post-traumatic stress disorder (PTSD): MDMA therapy has been extensively researched as a treatment option for PTSD. Several clinical trials have shown that MDMA-assisted therapy can provide significant reductions in PTSD symptoms, including reliving avoidance behaviors and hyperarousal.
  2. Anxiety disorders: Research suggests that MDMA therapy may help treat a variety of anxiety disorders, including social anxiety disorder and generalized anxiety disorder. It can lead to improvements in anxiety symptoms, social skills and emotional well-being.
  3. Depression: While research on MDMA therapy for depression is still in its early stages, there are indications that it may be a potential treatment option. There are studies suggesting that MDMA-assisted therapy may have positive effects on mood, self-acceptance, and empathy, which may help reduce depressive symptoms.
  4. Autism: Some studies have looked at the effects of MDMA therapy in adults with autism. Although limited research is still available, preliminary results show that MDMA may help reduce social anxiety and improve social skills and empathy.
  5. Addiction Disorders: MDMA therapy has been investigated as a potential treatment for substance use disorders, such as alcoholism and post-traumatic drug-related disorder. It can help gain insight into the underlying causes of addiction and increase motivation for behavior change.
  6. Relationship problems: Some studies have looked at the effects of MDMA therapy on relationship problems, particularly in couples. MDMA can help promote empathy, communication, and connection between partners, which can help improve relationship dynamics.
  7. Palliative care: Studies are ongoing on the role of MDMA therapy in palliative care, particularly in reducing anxiety and improving quality of life in terminally ill patients. Preliminary results suggest positive effects on emotional well-being and acceptance of death.
  8. Obsessive Compulsive Disorder (OCD): Although there is limited research on MDMA therapy in OCD, there is some evidence that it may have therapeutic potential. MDMA can help reduce anxiety symptoms and rigid thought patterns, creating space for new perspectives and behavior change.

How does MDMA work during therapy?

MDMA works by mainly increasing the activity of dopamine, norepinephrine and serotonin. These neurotransmitters help regulate mood, energy, appetite, emotions, sexual activity and sleep patterns. MDMA therapy in the Netherlands currently only works with a legal analogue, which has the same effect. The detailed explanation of how MDMA and legal analogues work can be found via the page below.

Effect and safety of MDMA

The MDMA session

MDMA sessions are part of a pathway that includes several elements to ensure safety and efficacy. It starts with an extensive screening and intake process to determine if the person is suitable for the session and to determine any medical contraindications. After the intake, time is spent improving neurochemistry and mental preparation through small assignments and recommendations.

On the day of the MDMA session, time is allotted for discussing goals, managing expectations and giving tips on how to deal with different situations during the session. The session itself is characterized by alternating spoken and unspoken periods, for which it is advised to use an eye mask, for example, while listening to music.

After the session, a debriefing will take place to integrate the session and develop a better understanding of the experiences. This phase is of the utmost importance and is concluded with a telephone call one week after the session to ensure that the journey towards healing and personal growth is kept on track. In summary, a MDMA session is a complex process that requires thorough screening, preparation, session and integration.

Sign up for MDMA therapy

Filling in the intake is the first step towards an MDMA session. The intake also forms the basis for personal advice and an action plan for your session. Use the links below to continue.

Start intake | MDMA therapy information